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1

Cognitive Complaints in Motor Functional Neurological (Conversion) Disorders: A Focused Review and Clinical Perspective

Alluri, Priyanka R., Solit, Juliet, Leveroni, Catherine L., Goldberg, Katherine, Vehar, Julia V., Pollak, Lauren E., Colvin, Mary K., Perez, David L.

Journal:

Cognitive and Behavioral Neurology

Year:

2020

File:

PDF, 299 KB

2020

2

Development and application of Hsp90 inhibitors

David B. Solit, Gabriela Chiosis

Journal:

Drug Discovery Today

Year:

2008

Language:

english

File:

PDF, 257 KB

english, 2008

3

New Efficient Synthesis of Resorcinylic Macrolides via Ynolides: Establishment of Cycloproparadicicol as Synthetically Feasible Preclinical Anticancer Agent Based on Hsp90 as the Target

Yang, Zhi-Qiang, Geng, Xudong, Solit, David, Pratilas, Christine A., Rosen, Neal, Danishefsky, Samuel J.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 279 KB

english, 2004

4

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

Chang, Matthew T, Asthana, Saurabh, Gao, Sizhi Paul, Lee, Byron H, Chapman, Jocelyn S, Kandoth, Cyriac, Gao, JianJiong, Socci, Nicholas D, Solit, David B, Olshen, Adam B, Schultz, Nikolaus, Taylor, Ba

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

5

Comprehensive molecular characterization of salivary duct carcinoma reveals actionable targets and similarity to apocrine breast cancer

Dalin, M. G., Desrichard, A., Katabi, N., Makarov, V., Walsh, L. A., Lee, K.-W., Wang, Q., Armenia, J., West, L., Dogan, S., Wang, L., Ramaswami, D., Ho, A. L., Ganly, I., Solit, D., Berger, M. F., Sc

Journal:

Clinical Cancer Research

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

6

A Phase Ib Study of Alpelisib (BYL719), a PI3K -specific Inhibitor, with Letrozole in ER+/HER2-Negative Metastatic Breast Cancer

Mayer, I. A., Abramson, V., Formisano, L., Balko, J. M., Estrada, M. V., Sanders, M., Juric, D., Solit, D., Berger, M. F., Won, H., Li, Y., Cantley, L. C., Winer, E. P., Arteaga, C. L.

Journal:

Clinical Cancer Research

Year:

2016

Language:

english

File:

PDF, 2.54 MB

english, 2016

7

Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high grade serous ovarian and breast cancer

Matulonis, U.A., Wulf, G.M., Barry, W.T., Birrer, M., Westin, S.N., Farooq, S., Bell-McGuinn, K.M., Obermayer, E., Whalen, C., Spagnoletti, T., Luo, W., Liu, H., Hok, R.C., Aghajanian, C., Solit, D.B.

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 428 KB

english, 2016

8

Surgical treatment in myasthenia gravis

Cohn, Herbert E., Solit, Robert W., Schatz, Norman J., Schlezinger, Nathan, Fineberg, Charles

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

1974

File:

PDF, 4.26 MB

1974

9

Inverted urothelial papilloma and urothelial carcinoma with inverted growth are histologically and molecularly distinct entities

Almassi, Nima, Pietzak, Eugene J, Sarungbam, Judy, Tickoo, Satish K, Reuter, Victor E, Solit, David B, AlâAhmadie, Hikmat A

Journal:

The Journal of Pathology

Year:

2020

File:

PDF, 532 KB

2020

10

Total Synthesis as a Resource in the Discovery of Potentially Valuable Antitumor Agents: Cycloproparadicicol

Kana Yamamoto, Robert M. Garbaccio, Shawn J. Stachel, David B. Solit, Gabriela Chiosis, Neal Rosen, Samuel J. Danishefsky

Journal:

Angewandte Chemie

Year:

2003

Language:

english

File:

PDF, 141 KB

english, 2003

11

Total Synthesis as a Resource in the Discovery of Potentially Valuable Antitumor Agents: Cycloproparadicicol

Kana Yamamoto, Robert M. Garbaccio, Shawn J. Stachel, David B. Solit, Gabriela Chiosis, Neal Rosen, Samuel J. Danishefsky

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 141 KB

english, 2003

12

New Efficient Synthesis of Resorcinylic Macrolides via Ynolides: Establishment of Cycloproparadicicol as Synthetically Feasible Preclinical Anticancer Agent Based on Hsp90 as the Target.

Zhi-Qiang Yang, Xudong Geng, David Solit, Christine A. Pratilas, Neal Rosen, Samuel J. Danishefsky

Journal:

Year:

2004

File:

PDF, 11 KB

2004

13

Clinical experience with intravenous estramustine phosphate, paclitaxel, and carboplatin in patients with castrate, metastatic prostate adenocarcinoma

David B. Solit, Michael Morris, Susan Slovin, Tracy Curley, Lawrence Schwartz, Steven Larson, Michael W. Kattan, Beryl Hartley-Asp, Howard I. Scher, W. Kevin Kelly

Journal:

Year:

2003

Language:

english

File:

PDF, 87 KB

english, 2003

14

High-dose calcitriol, zoledronate, and dexamethasone for the treatment of progressive prostate carcinoma

Michael J. Morris, Oren Smaletz, David Solit, W. Kevin Kelly, Susan Slovin, Carlos Flombaum, Tracy Curley, Anthony Delacruz, Lawrence Schwartz, Martin Fleisher, Andrew Zhu, Meghan Diani, Mary Fallon,

Journal:

Year:

2004

Language:

english

File:

PDF, 97 KB

english, 2004

15

Proton MRS detects metabolic changes in hormone sensitive and resistant human prostate cancer models CWR22 and CWR22r

H. Carl Le, Mihaela Lupu, Khushali Kotedia, Neal Rosen, David Solit, Jason A. Koutcher

Journal:

Magnetic Resonance in Medicine

Year:

2009

Language:

english

File:

PDF, 494 KB

english, 2009

16

Instant imaging systems: Their value and application in scanning electron microscopy

Journal:

Year:

1969

Language:

english

File:

PDF, 49 KB

english, 1969

17

Targeting Wide-Range Oncogenic Transformation via PU24FCl, a Specific Inhibitor of Tumor Hsp90

Maria Vilenchik, David Solit, Andrea Basso, Henri Huezo, Brian Lucas, Huazhong He, Neal Rosen, Claudia Spampinato, Paul Modrich, Gabriela Chiosis

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 322 KB

english, 2004

18

KRAS and BRAF: drug targets and predictive biomarkers

Efsevia Vakiani, David B Solit

Journal:

The Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 230 KB

english, 2011

19

A polyvalent vaccine for high-risk prostate patients: “are more antigens better?”

Susan F. Slovin, Govind Ragupathi, Celina Fernandez, Meghan Diani, Matthew P. Jefferson, Andrew Wilton, W. Kevin Kelly, Michael Morris, David Solit, Henrik Clausen, Philip Livingston, Howard I. Scher

Journal:

Cancer Immunology, Immunotherapy

Year:

2007

Language:

english

File:

PDF, 590 KB

english, 2007

20

A phase I trial of intermittent high-dose gefitinib and fixed-dose docetaxel in patients with advanced solid tumors

Matthew G. Fury, David B. Solit, Yungpo Bernard Su, Neal Rosen, F. M. Sirotnak, Robert P. Smith, Christopher G. Azzoli, Jorge E. Gomez, Vincent A. Miller, Mark G. Kris, Barbara A. Pizzo, Roxanne Henry

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2007

Language:

english

File:

PDF, 387 KB

english, 2007

21

The “SWOT” of BRAF Inhibition in Melanoma: RAF Inhibitors, MEK Inhibitors or Both?

Moriah H. Nissan, David B. Solit

Journal:

Current Oncology Reports

Year:

2011

Language:

english

File:

PDF, 409 KB

english, 2011

22

Managed Care Managing Breast Cancer: DCIS as the Paradigm (The Fox Is Guarding the Chickencoop!)

Richard L. Solit, Gordon F. Schwartz

Journal:

The Breast Journal

Year:

1997

Language:

english

File:

PDF, 544 KB

english, 1997

23

Drug discovery: How melanomas bypass new therapy

Solit, David, Sawyers, Charles L.

Journal:

Year:

2010

Language:

english

File:

PDF, 223 KB

english, 2010

24

BRAF mutation predicts sensitivity to MEK inhibition

Solit, David B., Garraway, Levi A., Pratilas, Christine A., Sawai, Ayana, Getz, Gad, Basso, Andrea, Ye, Qing, Lobo, Jose M., She, Yuhong, Osman, Iman

Journal:

Year:

2005

Language:

english

File:

PDF, 530 KB

english, 2005

25

Tracing cancer networks with phosphoproteomics

Solit, David B, Mellinghoff, Ingo K

Journal:

Nature Biotechnology

Year:

2010

Language:

english

File:

PDF, 565 KB

english, 2010

26

Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo

Henke, Erik, Perk, Jonathan, Vider, Jelena, de Candia, Paola, Chin, Yvette, Solit, David B, Ponomarev, Vladimir, Cartegni, Luca, Manova, Katia, Rosen, Neal

Journal:

Nature Biotechnology

Year:

2008

Language:

english

File:

PDF, 688 KB

english, 2008

27

Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors

Smith-Jones, Peter M, Solit, David B, Akhurst, Timothy, Afroze, Farzana, Rosen, Neal, Larson, Steven M

Journal:

Nature Biotechnology

Year:

2004

Language:

english

File:

PDF, 408 KB

english, 2004

28

Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth

Chandarlapaty, S, Scaltriti, M, Angelini, P, Ye, Q, Guzman, M, Hudis, C A, Norton, L, Solit, D B, Arribas, J, Baselga, J

Journal:

Year:

2009

Language:

english

File:

PDF, 639 KB

english, 2009

29

Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2

Basso, Andrea D, Solit, David B, Munster, Pamela N, Rosen, Neal

Journal:

Year:

2002

Language:

english

File:

PDF, 280 KB

english, 2002

30

Will Hsp90 Inhibitors Prove Effective in BRAF-Mutant Melanomas?

Catalanotti, F., Solit, D. B.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 438 KB

english, 2012

31

A phase 2 study of the insulin-like growth factor-1 receptor inhibitor MK-0646 in patients with metastatic, well-differentiated neuroendocrine tumors

Diane L. Reidy-Lagunes, Efsevia Vakiani, Michal F. Segal, Ellen M. Hollywood, Laura H. Tang, David B. Solit, M. Catherine Pietanza, Marinela Capanu, Leonard B. Saltz

Journal:

Year:

2012

Language:

english

File:

PDF, 717 KB

english, 2012

32

Population pharmacokinetic analysis of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) in adult patients with solid tumors

Aregbe, Abdulateef O., Sherer, Eric A., Egorin, Merrill J., Scher, Howard I., Solit, David B., Ramanathan, Ramesh K., Ramalingam, Suresh, Belani, Chandra P., Ivy, Percy S., Bies, Robert R.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 215 KB

english, 2012

33

The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells

Qing-Bai She, David B. Solit, Qing Ye, Kathryn E. O’Reilly, Jose Lobo, Neal Rosen

Journal:

Year:

2005

Language:

english

File:

PDF, 639 KB

english, 2005

34

4E-BP1 Is a Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways that Integrates Their Function in Tumors

Qing-Bai She, Ensar Halilovic, Qing Ye, Wei Zhen, Senji Shirasawa, Takehiko Sasazuki, David B. Solit, Neal Rosen

Journal:

Year:

2010

Language:

english

File:

PDF, 1.45 MB

english, 2010

35

HGF/MET rescues Gefitinib treated non-small cell lung cancer cells carrying an activating EGFR mutation

Mark Y. Sun, Thomas Bachleitner-Hofmann, Chin-Tung Chen, David B. Solit, Martin R. Weiser

Journal:

Journal of the American College of Surgeons

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

36

Acquired KRAS mutation as mechanism of resistance to EGFR inhibition in colorectal cancer

David Liska, Manickam Janakiraman, Chin-Tung Chen, Pei-Rong Ding, David B. Solit, Martin R. Weiser

Journal:

Journal of the American College of Surgeons

Year:

2010

Language:

english

File:

PDF, 95 KB

english, 2010

37

Hsp90 as a therapeutic target in prostate cancer

David B Solit, Howard I Scher, Neal Rosen

Journal:

Seminars in Oncology

Year:

2003

Language:

english

File:

PDF, 143 KB

english, 2003

38

Hsp90: the vulnerable chaperone

Gabriela Chiosis, Maria Vilenchik, Joungnam Kim, David Solit

Journal:

Drug Discovery Today

Year:

2004

Language:

english

File:

PDF, 317 KB

english, 2004

39

HER-Kinase-Directed Therapy of Prostate Cancer

David B. Solit, David B. Agus

Journal:

The Prostate Journal

Year:

2001

Language:

english

File:

PDF, 198 KB

english, 2001

40

Translational medicine: Primed for resistance

Solit, David B., Jänne, Pasi A.

Journal:

Year:

2012

Language:

english

File:

PDF, 658 KB

english, 2012

41

BRAF Mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer

Rachel N. Grisham, Gopa Iyer, Karuna Garg, Deborah DeLair, David M. Hyman, Qin Zhou, Alexia Iasonos, Michael F. Berger, Fanny Dao, David R. Spriggs, Douglas A. Levine, Carol Aghajanian, David B. Solit

Journal:

Year:

2012

Language:

english

File:

PDF, 463 KB

english, 2012

42

Therapeutic strategies for inhibiting oncogenic BRAF signaling

Ensar Halilovic, David B Solit

Journal:

Current Opinion in Pharmacology

Year:

2008

Language:

english

File:

PDF, 446 KB

english, 2008

43

Oncogenic RAF: a brief history of time

David Solit, Neal Rosen

Journal:

Pigment Cell & Melanoma Research

Year:

2010

Language:

english

File:

PDF, 40 KB

english, 2010

44

Resistance to MEK Inhibitors: Should We Co-Target Upstream?

Poulikakos, P. I., Solit, D. B.

Journal:

Science Signaling

Year:

2011

Language:

english

File:

PDF, 493 KB

english, 2011

45

Induction of Cutaneous Squamous Cell Carcinomas by RAF Inhibitors: Cause for Concern?

Lacouture, M. E., O'Reilly, K., Rosen, N., Solit, D. B.

Journal:

Journal of Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 81 KB

english, 2012

46

12th Annual Meeting of the Society of Urologic Oncology (SUO) Bladder Cancer Sessions I and II summary report

Chang, Sam S., Dinney, Colin P.N., Donat, S. Machele, Dahm, Philipp, Gore, John L., Lotan, Yair, Parekh, Dipen J., Solit, David B., O'Donnell, Peter H., Feng, Felix Y., Hansel, Donna, Milowsky, Matthe

Journal:

Urologic Oncology: Seminars and Original Investigations

Year:

2012

Language:

english

File:

PDF, 132 KB

english, 2012

47

56 Hsp90-targeted therapy for small cell lung cancer

G. Chiosis, N. Rosen, J. Kim, J. Aguirre, D. Solit, M. Vilenchik

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 140 KB

english, 2004

48

348 HER2 imaging as a non-invasive pharmacodynamic marker of Hsp90 inhibition

D.B. Solit, P.M. Smith-Jones, H. Scher, S.M. Larson, N. Rosen

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 147 KB

english, 2004

49

349 Restoration of PTEN-expression in tumor cells causes them to depend on EGFR for suppression

Q.-B. She, D. Solit, Q. Ye, K. O'Reilly, M. Moasser, N. Rosen

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 288 KB

english, 2004

50

388 The abrogation of rapamycin-induced AKT activity by the small molecule IGF-IR inhibitor, AEW541, and the enhanced antitumor activity of combined mTOR and IGF-IR inhibition

K. O'Reilly, Q. She, H. Lane, F. Hofmann, D. Solit, N. Rosen

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 147 KB

english, 2004

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